BUFFERING FUNCTION: A GENERAL APPROACH FOR BUFFER BEHAVIOR

Abstract

Buffering systems are widely used in all areas of science that involve the use of aqueous solutions, such as pharmaceutical, environmental and analytical chemistry. However, there are several approaches and parameters that can be employed to try to explain buffering behavior, such as the Van Slyke buffer value, Kolthoff’s buffer capacity, acidity, alkalinity, and others, although they are unable to provide a global explanation of it. In this paper, we propose the Buffering Function, which is a fundamental equation that enables explanation of all types of buffering behavior and existing parameters, without use of the Henderson-Hasselbalch approach