SÍNTESE E CARACTERIZAÇÃO DE NANOESFERAS DE POLIESTIRENO PARA ENCAPSULAMENTO DE NANOPARTICULADO MAGNÉTICO

Authors

  • Gustavo Gonzaga Monteiro Elyseu
  • Marcello Rosa Dumont
  • Roberta Viana Ferreira

DOI:

https://doi.org/10.18540/jcecvl3iss8pp1259-1270

Keywords:

Nanoesfera, Poliestireno, Hipertermia

Abstract

Nanopartículas com propriedades magnéticas podem atuar no combate oncológico por meio da hipertermia terapêutica a qual provoca a desnaturação de proteínas e, portanto, o enfraquecimento de células tumorais. A principal vantagem desta técnica é efeitos colaterais mais brandos do que os tratamentos convencionais. Objetivando uma ativação indesejada do sistema imune este trabalho propõe desenvolver uma rota para a obtenção de partículas nanométricas de poliestireno (PS) visando encapsular tais partículas. Foi utilizada uma rota livre de emulsificantes o que garantiria uma maior pureza do sistema. O material sintetizado foi analisado através microscopia eletrônica de varredura, granulometria por difração a laser, análise térmica e espectroscopia no infravermelho. Foi confirmada a obtenção de poliestireno no formato esférico com tamanho médio de partícula de 317 nm ± 58 nm adequada para o uso em sistemas biológicos

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References

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Published

2017-10-04

How to Cite

Elyseu, G. G. M., Dumont, M. R., & Ferreira, R. V. (2017). SÍNTESE E CARACTERIZAÇÃO DE NANOESFERAS DE POLIESTIRENO PARA ENCAPSULAMENTO DE NANOPARTICULADO MAGNÉTICO. The Journal of Engineering and Exact Sciences, 3(8), 1259–1270. https://doi.org/10.18540/jcecvl3iss8pp1259-1270

Issue

Section

Materials Science and Engineering